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A Great Challenge Undertaken by Researchers at GC Cell
We will not stop as long as life goes on.

Cell Therapy Products

Our cytotherapy laboratory, founded under the mission of commercialization of cell therapy products, is spurring R&D
based on the foundation of the best technological prowess and excellent research talents in the future industry of cell
therapy. We have applied/registered for multiple patents related to cytotherapy technologies, continuing to secure
intellectual properties and contributing to international academic journals, receiving overseas recognition for research
feats Using our experience in immunocyte therapy development as our foothold, we shall contribute to improving the
quality of life for humankind by devoting ourselves to next-generation cell/gene therapy products and stem cell
research toward developing various cell therapy products.

Technologies

01

01

NK-specific CAR Platforms

· scFV-CAR-NK
· NCR-CAR-NK
· Proprietary NK-specific co-stimulatory domains

02

02

Genetic Engineering

· Used for generating proprietary CAR constructs
· 3rd generation lentivirus
· Knock-out of gene of interest

03

03

Mass Culturing

· Patent-protected mass culture system using a bioreactor
· Patent-protected e-feeder cell system for NK expansion
· Automatic process developmen
· GMP production

04

04

Cryopreservation

· Patent-protected
· Extended stability (~2 years)
· Global shipping available

05

05

International Standard Cord Blood

· Use of FDA approved CBUs
· Easy-to-supply, Stable, and safe
· Low donor-donor variation

5 Technology strengths of GC Cell are the key building blocks for
cell and gene therapy research and development

Partners

Low cost of goods
Direct Killing
directKilling
  • · Manufacturing
  • · Feeder cell system
  • · Cord blood NK cell
  • · Bioreactor
서울아산병원 로고 서울대학교병원 로고
Higher efficiency
Antibody-mediated
Killing
Higher efficiency
  • · Antibody combination
  • · Rituxan, Herceptin, Cetuximab etc.
  • · Immune Checkpoint Inhibitor: anti-PD-1 etc.
서울아산병원 로고 서울대학교병원 로고 서울대학교병원 로고
Higher efficiency & safety
Targeted-activated
Killing
Higher efficiency
  • · scFV-CAR-NK
  • · NCR-CAR-NK
  • · NK specific intra cellular domain
abclon 로고 artiva 로고 msd 로고 lentigen 로고
Higher persistency & efficiency
Gene-edited
efficiency
  • · Long-lasting
  • · Enhanced efficacy by removing inhibitory the inhibitory molecule
abclon 로고
Unlimited expansion
iPSc-derived
Unlimited expansion
  • · iPSc-NK product platform
  • · Mass produce homogeneous
  • · Cost-effective